Table 1 Significant associations of the SNP with NSCL/P risk in the entire sample.

Chr.	SNP	Stage	Region	MAF		Case	Control	OR (CI 95%)	P	P _meta ^*	P _meta**	P _meta ^#
Chr.	SNP	Stage	Region	Case	Control	Case	Control	OR (CI 95%)	P	P _meta ^*	P _meta**	P _meta ^#
10	rs17095681	GWAS	Sichuan	0.064	0.123	59/439	100/330	0.42 (0.29–0.60)	2.52E-6			3.80E-9
		Validation a	Guangdong	0.070	0.113	64/431	107/389	0.53 (0.38–0.75)	2.91E-4	8.50E-5	1.50E-5
		Validation b	Sichuan	0.081	0.097	71/405	84/395	0.82 (0.58–1.16)	2.67E-1
		Validation c	Nanjing	0.097	0.104	79/368	105/412	0.84 (0.61–1.17)	2.99E-1
		Validation d	Ningxia (Han)	0.077	0.115	36/211	89/328	0.62 (0.40–0.95)	2.71E-2
		Validation e	Ningxia (Hui)	0.059	0.090	31/231	58/275	0.64 (0.40–1.03)	6.42E-2

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