Figure 14 | Scientific Reports

Figure 14

From: Shengmai Formula suppressed over-activated Ras/MAPK pathway in C. elegans by opening mitochondrial permeability transition pore via regulating cyclophilin D

Figure 14

SM enhanced germ cell apoptosis in let-60 (gf) mutants.

(A) Worms were stained by 50 μM SYTO 12 after treated with SM for 48 hours. Germ cell corpse is indicated by white arrows. Con and C: control. SMH, 12 mg/mL; SMHH, 24 mg/mL; SMHHH, 48 mg/mL. NAC, 2.5 mM N-Acety-L-Cysteine; PQ, 0.5 mM paraquat. Scale bar, 50 μm. (B) Quantified the number of germ cell corpse of each group. Data is presented as the mean ± SD of at least three independent experiments. Bars with different letters indicated that there was a significant difference at a level of 0.05 among groups.

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