Table 1 Clinical characteristics of the subjects.

From: Downregulation of peroxiredoxin-3 by hydrophobic bile acid induces mitochondrial dysfunction and cellular senescence in human trophoblasts

 

Normal (n = 46)

ICP (n = 70)

p value

Maternal age (years)

30.5 ± 3.2

30.2 ± 4.0

0.648

BMI of mother

21.3 ± 2.5

21.8 ± 3.0

0.359

Gravidity

1.7 (1–4)

1.7 (1–7)

0.473

Parity

1.3 (1–2)

1.2 (1–3)

0.063

Gestational age (weeks)

38.9 ± 1.0

37.6 ± 1.6

<0.0001

TBA at delivery (μmol/L)

5.8 ± 2.9

29.4 ± 24.1

<0.0001

Birth weight (g)

3368.6 ± 354.6

3056.7 ± 395.1

<0.0001

Placenta weight (g)

538.1 ± 77.4

488.0 ± 91.7

<0.01

Apgar at 5 min

9.98 (9–10)

9.94 (7–10)

0.545

Sex of neonate

 Male (%)

18 (39.1)

39 (55.7)

0.081

 Female (%)

28 (60.9)

31 (44.3)

 
  1. Abbreviation: ICP, intrahepatic cholestasis of pregnancy; BMI, body mass index; TBA, total bile acids. Values are given as mean ± SD, mean (range), or N (percent).
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