Table 2 Demographic and Clinical Characteristics of IPF Subjects Stratified by Plasma Chemokine (C-X-C motif) Ligan 1 Levels.

From: Clinical Association of Chemokine (C-X-C motif) Ligand 1 (CXCL1) with Interstitial Pneumonia with Autoimmune Features (IPAF)

 

Lowest CXCL1

Highest CXCL1

P

N

28

10

Age, yr

55 ± 2.6

52 ± 2.8

0.7871

Male

15(54%)

6(60%)

0.4509

FVC, % predicted

70 ± 2.6

68 ± 3.6

0.7241

FEV1, % predicted

78 ± 2.7

68 ± 4.7

0.0697

FEV1/FVC

0.80 ± 0.019

0.77 ± 0.038

0.4940

DLCO, %predicted

51 ± 2.3**

34 ± 2.9**

0.0003

FibMax

137.2 ± 14.7**

222.5 ± 28.4**

0.0069

ESR, mm/h

72.4 ± 3.3**

92.8 ± 5.2**

0.0023

  1. Data are presented as the means ± SE and in parentheses (median, minimum-to-maximum ranges). IIP: idiopathic interstitial pneumonia; IPAF: interstitial pneumonia with autoimmune features; N: number; yr: years; FVC: forced vital capacity; FEV1: forced expiratory volume in 1 second; DLCO: carbon monoxide diffusing capacity of the lung; ESR: erythrocyte sedimentation rate.