Figure 5

STC analysis of the differentially expressed lncRNAs related to malignant EOC.
(A) The patterns of differentially expressed lncRNAs were analyzed, and sixteen model profiles were summarized. Each box represents a model expression profile. The upper number is the mode profile number which is used to summarize the different gene expression patterns. In total, 5 expression patterns of genes exhibited significant p-values (p < 0.05). Clusters are ordered based on the number of genes assigned. The number of transcripts assigned to each model profile was used as the estimate of the number of co-expressed lncRNAs, which was computed by the clustering method. (B) The most significant pattern of profile No. 15 is presented. A in the horizontal axis represents normal ovarian tissues, B represents benign ovarian cyst, and C denotes malignant EOC tissues. The vertical axis displays the time series of gene expression levels for the gene after Log2 normalized transformation.