Figure 7 | Scientific Reports

Figure 7

From: Anticancer activity of a monobenzyltin complex C1 against MDA-MB-231 cells through induction of Apoptosis and inhibition of breast cancer stem cells

Figure 7

(a) MDA-MB-231 cancer stem cells identification. MDA-MB-231 CSCs were recognized by expression of CD44+ and low expression of CD24-/low in quadrant examination (CD44+/CD24-/low). (b) Mammosphere formation of MDA-MB-231 cancer stem cells: (A) and (B) show the size of mammospheres containing MDA-MB-231 cancer stem cells on day 5 and day 7, respectively. (c) reduction in the size of primary mammospheres in treated MDA-MB-231 cancer stem cells: Cancer stem cells were treated with complex C1 at 1 (B), 2 (C), and 4 (D) μg/mL concentrations. A indicates untreated cells. Complex C1 reduced the size of the primary mammospheres in treated MDA-MB-231 cancer stem cells. Each experiment was performed in triplicate.

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