Table 3 Associations between the IGF1 rs5742714 polymorphism and RCC patients’ survival.

From: Genetic variation in IGF1 predicts renal cell carcinoma susceptibility and prognosis in Chinese population

IGF1 rs5742714

Patients (N = 311)

Deaths (N = 33)

5-yr survival* (%)

Log-Rank P

HR (95% CI)†

Codominant model

GG

205

27

77.1%

 

1.00 (reference)

GC

93

5

88.9%

0.031

0.36 (0.14–0.94)

CC

13

1

85.7%

0.440

0.47 (0.06–3.51)

Additive model

   

0.046

0.45 (0.21–0.99)

Dominant model

GG

205

27

77.1%

0.025

1.00 (reference)

GC/CC

106

6

88.0%

 

0.36 (0.14–0.93)

  1. HR: hazards ratio; CI: confidence interval.
  2. *Proportion of survival derived from Kaplan-Meier analysis.
  3. †Adjusted for age, gender, smoking, drinking status, diabetes and hypertension as well as tumor grade and clinic stage.
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