Table 4 Univariate and multivariate Cox proportional hazard analysis of death risk in patients with RCC.

From: Genetic variation in IGF1 predicts renal cell carcinoma susceptibility and prognosis in Chinese population

Parameters

Univariate

Multivariate†

HR (95% CI)*

P value

HR (95% CI)a

P value

Age (≤56 vs. >56)

1.68 (0.83–3.37)

0.147

  

Gender (female vs. male)

0.89 (0.44–1.82)

0.758

  

Smoking status (never vs. ever)

0.97 (0.47–2.00)

0.929

  

Drinking status (never vs. ever)

1.33 (0.63–2.80)

0.458

  

Diabetes (no vs. yes)

0.66 (0.20–2.16)

0.493

  

Hypertension (no vs. yes)

1.53 (0.77–3.05)

0.222

  

Tumor grade (III/IV vs. I/II)

8.88 (3.66–21.52)

<0.001

4.24 (1.70–10.6)

0.002

Clinical stage (III/IV vs. I/II)

20.28 (8.78–46.87)

<0.001

15.8 (6.28–39.5

<0.001

IGF rs5742714 (GC/CC vs. GG)

0.37 (0.16–0.91)

0.031

0.36 (0.14–0.93)

0.035

  1. *HR: hazards ratio; CI: confidence interval.
  2. †In this multivariate analysis age, gender, smoking, drinking status, diabetes, hypertension, tumor stage, clinic stage and the number of variant alleles were included.
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