Table 2 The univariate and multivariate analysis of adenocarcinoma of appendix according to AJCC TNM staging system.
From: The Management and Prognostic Prediction of Adenocarcinoma of Appendix
Stage I–III | Stage IV | |||||||
---|---|---|---|---|---|---|---|---|
N | Univariate | Multivariate | N | Univariate | Multivariate | |||
P value | P value | Hazard Ratio | P value | P value | Hazard Ratio | |||
Age | ||||||||
Less than 50 | 179 | 121 | ||||||
50–75 | 580 | 258 | ||||||
More than 75 | 218 | <0.001 | <0.001 | 1.531–2.326 | 48 | 0.633 | ||
Gender | ||||||||
Male | 551 | 158 | ||||||
Female | 426 | 0.815 | 269 | 0.246 | ||||
Race | ||||||||
White | 792 | 353 | ||||||
Black | 120 | 35 | ||||||
Other | 65 | 0.895 | 39 | 0.063 | ||||
Marital status | ||||||||
Single | 350 | 115 | ||||||
Married | 627 | 0.002 | 0.001 | 0.505–0.849 | 272 | 0.688 | ||
T Stage | ||||||||
Tis/T1/T2 | 235 | 24 | ||||||
T3 | 441 | 77 | ||||||
T4 | 301 | <0.001 | <0.001 | 1.219–1.773 | 326 | 0.116 | ||
Examined lymph nodes | ||||||||
Less than 12 | 399 | 236 | ||||||
More than 12 | 578 | <0.001 | <0.001 | 0.459–0.775 | 191 | 0.554 | ||
Lymph nodes status | ||||||||
N0 | 773 | 273 | ||||||
N1 | 137 | 74 | ||||||
N2 | 67 | <0.001 | <0.001 | 1.467–2.169 | 80 | <0.001 | <0.001 | 1.423–2.067 |
Grade | ||||||||
G1 | 265 | 140 | ||||||
G2 | 565 | 180 | ||||||
G3/G4 | 147 | 0.002 | 0.043 | 1.007–1.536 | 107 | <0.001 | <0.001 | 1.303–2.021 |
Tumor size | ||||||||
<20 | 319 | 71 | ||||||
20–50 | 439 | 170 | ||||||
50–80 | 168 | 112 | ||||||
>80 | 51 | 0.481 | 74 | 0.245 | ||||
Resection | ||||||||
local excision | 336 | 136 | ||||||
Hemicolectomy | 612 | 224 | ||||||
Total colectomy | 29 | 0.086 | 67 | 0.934 | ||||
Mucinous | ||||||||
Positive | 382 | 302 | ||||||
Negative | 595 | 0.365 | 125 | 0.001 | 0.747 | 0.682–1.316 |