Table 2 The univariate and multivariate analysis of adenocarcinoma of appendix according to AJCC TNM staging system.

From: The Management and Prognostic Prediction of Adenocarcinoma of Appendix

 

Stage I–III

Stage IV

N

Univariate

Multivariate

N

Univariate

Multivariate

P value

P value

Hazard Ratio

P value

P value

Hazard Ratio

Age

 Less than 50

179

   

121

   

 50–75

580

   

258

   

 More than 75

218

<0.001

<0.001

1.531–2.326

48

0.633

  

Gender

 Male

551

   

158

   

 Female

426

0.815

  

269

0.246

  

Race

 White

792

   

353

   

 Black

120

   

35

   

 Other

65

0.895

  

39

0.063

  

Marital status

 Single

350

   

115

   

 Married

627

0.002

0.001

0.505–0.849

272

0.688

  

T Stage

 Tis/T1/T2

235

   

24

   

 T3

441

   

77

   

 T4

301

<0.001

<0.001

1.219–1.773

326

0.116

  

Examined lymph nodes

 Less than 12

399

   

236

   

 More than 12

578

<0.001

<0.001

0.459–0.775

191

0.554

  

Lymph nodes status

 N0

773

   

273

   

 N1

137

   

74

   

 N2

67

<0.001

<0.001

1.467–2.169

80

<0.001

<0.001

1.423–2.067

Grade

 G1

265

   

140

   

 G2

565

   

180

   

 G3/G4

147

0.002

0.043

1.007–1.536

107

<0.001

<0.001

1.303–2.021

Tumor size

 <20

319

   

71

   

 20–50

439

   

170

   

 50–80

168

   

112

   

 >80

51

0.481

  

74

0.245

  

Resection

 local excision

336

   

136

   

 Hemicolectomy

612

   

224

   

 Total colectomy

29

0.086

  

67

0.934

  

Mucinous

 Positive

382

   

302

   

 Negative

595

0.365

  

125

0.001

0.747

0.682–1.316