Figure 1 | Scientific Reports

Figure 1

From: Brusatol inhibits HIF-1 signaling pathway and suppresses glucose uptake under hypoxic conditions in HCT116 cells

Figure 1

BRU inhibits proliferation of HCT116 cells.

(A) HCT116 cells were exposed to different concentrations of BRU for 24 h, followed by MTT assay to measure cell viability. Data was presented as means ± S.D. (n = 6). ***p < 0.001 versus 0 nM BRU-treated group. (B) HCT116 cells were treated with DMSO and BRU (60 nM) for 12 h and 24 h and amount of living cells were detected by trypan blue exclusion assay. (C) HCT116 cells were exposed to different concentrations of BRU for 24 h and images were captured under phase contrast microscopy to observe cell morphology. Scale bars, 100 μm.

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