Figure 3 | Scientific Reports

Figure 3

From: Rats overexpressing the dopamine transporter display behavioral and neurobiological abnormalities with relevance to repetitive disorders

Figure 3

Neurotransmitter contents and compensatory mechanisms.

Post mortem tissue (a) dopamine and (b) DOPAC contents as well as (c) dopamine turnover in corticostriatal and associated network regions in wt (n = 7) and DAT-tg rats (n = 10). mPFC: medial prefrontal cortex, OFC: orbitofrontal cortex, Nacc: nucleus accumbens, CPu: caudate putamen, GP: globus pallidus, Hipp: hippocampus, Thal: dorsomedial thalamus, STN: subthalamic nucleus. (d) Monoamine oxidase (MAO) activity of striatal tissues in wt (n = 8) and DAT-tg rats (n = 7). All data are means ± s.e.m. Asterisk (*) indicates significant difference to wt rats with p < 0.05.

Back to article page