Table 1 Serological biochemical markers in the TA2-nHP66 group.

From: An effective treatment of experimental osteomyelitis using the antimicrobial titanium/silver-containing nHP66 (nano-hydroxyapatite/polyamide-66) nanoscaffold biomaterials

Biomarkers

Preoperative

Week 1

Week 2

Week 4

Week 8

Week 12

ALT(U/L)

49.40 ± 10.69

55.46 ± 9.79*

53.33 ± 7.35*

51.00 ± 11.11*

48.20 ± 5.63*

47.60 ± 8.79*

AST(U/L)

26.20 ± 4.97

28.57 ± 8.61*

29.37 ± 6.54*

27.00 ± 11.62*

24.60 ± 7.23*

26.00 ± 7.65*

BUN(mmol/L)

6.20 ± 2.49

6.87 ± 3.74*

6.95 ± 4.76*

6.40 ± 2.51*

6.20 ± 4.21*

6.40 ± 3.36*

CREA(μmol/L)

87.80 ± 19.69

93.36 ± 14.74*

90.17 ± 18.53*

82.20 ± 13.88*

93.00 ± 18.97*

88.40 ± 13.01*

ALP(U/L)

17.53 ± 5.67

21.75 ± 8.37*

23.18 ± 6.35*

20.76 ± 11.25*

23.15 ± 5.77*

21.37 ± 7.53*

  1. Serum biochemical markers in the TA2-nHP66 group (M ± S, n = 5).
  2. ALT, alanine transaminase; AST, aspartate aminotransferase; BUN, blood urea nitrogen; CREA, creatinine; ALP, alkaline phosphatase. *p > 0.05.