Figure 7 | Scientific Reports

Figure 7

From: Aptamer-PEG-modified Fe3O4@Mn as a novel T1- and T2- dual-model MRI contrast agent targeting hypoxia-induced cancer stem cells

Figure 7

In vivo targeted dual mode MR imaging.

(A) T1WI MR images and signal intensity analysis for T1WI MRI of Panc-1 tumour-bearing nude mice before and after injection of D-Fe3O4@PMn NPs in a 3.0 T MR system. (B) T2WI MR images and signal intensity analysis for T2WI MR images of Panc-1 tumour-bearing nude mice before and after injection of D-Fe3O4@PMn NPs in a 3.0 T MR system. (C) H&E staining images of major organs (heart, lung, liver, spleen, and kidney) of Panc-1 tumour-bearing nude mice in groups of PBS and D-Fe3O4@PMn NPs (the scale bar is 50 μm).

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