Table 3 Summary of the Datasets and Comparisons.
From: Molecular Characterization of Pediatric Restrictive Cardiomyopathy from Integrative Genomics
Data Set/GEO Number | Description | Type | Source |
|---|---|---|---|
NDR | Controls from NDR, n = 5 | RNA-Seq | Experimentally Determined |
RCM | RCM subjects, n = 4 | RNA-Seq | Experimentally Determined |
GSE48166 | adult ICM (n = 15) and adult non-failing control hearts (n = 15) | RNA-Seq | Gene Expression Omnibus |
GSE55296 | ICM (n = 8) and DCM (n = 8) compared with non-failing control hearts (n = 8) | RNA-Seq | PMID: 24599027 |
GSE57338 | non-failing left ventricle (ages 8-80yrs, n = 135) | HuGene-1_1-st | PMID: 25528681 |
GSE36761 | left vs right ventricle | RNA-Seq | PMID: 24459294 |
Combined Sets Names | Data Set | ||
Non-failing | NDR and non-failing controls from GSE48166 and GSE55296, n = 28 | ||
Cardiomyopathy | RCM and ICM (GSE48166 and GSE55296) and DCM (GSE55296), n = 35 | ||
Comparison Name | Description | Comparison | |
Common Cardiomyopathy | Comparison of all cardiomyopathy samples to non-failing hearts | Non-failing vs Cardiomyopathy | |
NDR vs RCM | Comparison of RCM to control hearts | NDR vs RCM | |
RCM specific | Comparison of RCM to common cardiomyopathy signatures | RCM vs Common Cardiomyopathy |