Figure 8 | Scientific Reports

Figure 8

From: Identification of cancer risk lncRNAs and cancer risk pathways regulated by cancer risk lncRNAs based on genome sequencing data in human cancers

Figure 8

The workflow of this study.

Step one, lncRNAs expression screening and pathways-lncRNA information. First, six cancer datasets were used as training datasets and ten cancer datasets were used as validation datasets. Then RPKM values were calculated for each lncRNA or mRNA. Step two, identification of cancer risk pathways and cancer risk lncRNAs according to Wilcoxon signed-rank test of Δe for all DE lncRNAs/genes within a pathway. Step three, Evaluation of the performance with cancer risk lncRNAs based on SVM and survival analysis.

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