Table 4 Titin-N fragment levels in urine of healthy adult volunteers.

From: Establishment of a highly sensitive sandwich ELISA for the N-terminal fragment of titin in urine

Sample (age, sex)

Values

Result (pmlo/L)

Mean result (pmol/L)

Std. Dev.

CV (%)

Dilution

Calculated Titin-N (nmol/L)

Cr (mg/dl)

Titin-N/Cr (pmol/mg/dl)

1 (39, M)

0.274

282.4

289.9

10.48

3.6

5

1.45

121.29

1.20

0.289

297.3

2 (58, M)

0.673

744.3

765.1

29.42

3.8

5

3.83

148.21

2.58

0.712

785.9

3 (39, M)

0.344

389.2

391.4

3.09

0.8

5

1.96

165.65

1.18

0.348

393.6

4 (28, M)

0.344

455.7

468.7

18.38

3.9

5

2.34

103.21

2.27

0.365

481.7

5 (50, M)

0.247

334.2

345.0

15.20

4.4

5

1.72

156.21

1.10

0.264

355.7

6 (38, M)

0.706

728.2

730.7

3.564

0.5

5

3.65

333.84

1.09

0.711

733.2

7 (70, M)

0.348

364.6

359.0

7.975

2.2

5

1.80

49.56

3.62

0.337

353.4

8 (42, M)

0.156

226.6

222.4

5.937

2.7

5

1.11

74.16

1.50

0.150

218.2

9 (34, M)

0.981

1004.3

995.3

12.737

1.3

5

4.98

229.45

2.17

0.963

986.3

10 (42, M)

0.471

490.2

482.1

11.519

2.4

5

2.41

195.84

1.23

0.455

474.0

11 (46, M)

1.020

1043.3

1039.3

5.655

0.5

5

5.20

201.00

2.59

1.012

1035.3

12 (47, M)

0.580

600.9

594.3

9.312

1.6

5

2.97

148.90

2.00

0.567

587.7

13 (37, M)

0.771

793.7

792.2

2.134

0.3

5

3.96

189.72

2.09

0.768

790.6

14 (44, M)

0.391

408.7

406.6

2.891

0.7

5

2.03

80.13

2.54

0.387

404.6

15 (59, M)

2.035

2048.9

2052.8

5.564

0.3

5

10.26

144.77

7.09

2.043

2056.7

16 (46, F)

0.115

123.3

120.1

4.465

3.7

5

0.60

30.49

1.97

0.109

117.0

17 (37, F)

0.131

140.1

142.7

3.706

2.6

5

0.71

46.35

1.54

0.136

145.3

18 (35, F)

0.539

559.3

552.7

9.329

1.7

5

2.76

124.13

2.23

0.526

546.1

  1. The concentrations of creatinine in urine samples were measured by the creatinase-sarcosine oxidase-POD method (Special Reference Laboratory Co., Tokyo, Japan). The value of Titin N- fragment concentration was corrected by the value of creatinine and is shown as creatinine ratio (pmol/mg · Cr) = Titin N-fragment(nmol/L) ÷ Cr(mg/dl) × 100.
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