Figure 2 | Scientific Reports

Figure 2

From: Down-regulation of common NFκB-iNOS pathway by chronic Thalidomide treatment improves Hepatopulmonary Syndrome and Muscle Wasting in rats with Biliary Cirrhosis

Figure 2

Effects of thalidomide on cirrhotic lungs.

(A,B) mRNA/protein expressions. (C) correlation between M1 macrophages (%) in BAL fluid and circulating CD16+ monocyte (%); (D) correlation between M1 macrophages (%) in BAL fluid and iNOS mRNA level in lung; (E) correlation between iNOS mRNA level in lung and relative pulmonary MVD; (F) total pulmonary nitric oxide (NOx) level; (G) correlation between pulmonary NOx level and AaPO2 (mmHg); (H) HPAECs tube formation after various treatments. #,##p < 0.05, 0.01 vs. S-V (buffer only group); *p < 0.05 vs. BDL-V; δp < 0.05 vs. TNFα groups; †p < 0.05 vs. TNFα + thalidomide (thal) groups.

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