Figure 6 | Scientific Reports

Figure 6

From: Down-regulation of common NFκB-iNOS pathway by chronic Thalidomide treatment improves Hepatopulmonary Syndrome and Muscle Wasting in rats with Biliary Cirrhosis

Figure 6

Schematic representative hypothesis for anti-sarcopenia and anti-angiogenesis effect of chronic thalidomide treatment on cirrhotic rats of our study.

Abbreviations: BDL: bile duct ligation; TNFα: tumor necrosis factor-alpha; MCP-1: monocyte chemoattractic protein-1; VEGF: vascular endothelial growth factor; iNOS: inducible nitric oxide synthase; NFκB: nuclear factor kappa B; HPAEC: human pulmonary artery endothelial cells; BAL: bronchoalveolar lavage; MVD: microvascular density; MHC: myosin heavy chain.

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