Table 2 Muscle wasting parameters (n = 7 in each group).

From: Down-regulation of common NFκB-iNOS pathway by chronic Thalidomide treatment improves Hepatopulmonary Syndrome and Muscle Wasting in rats with Biliary Cirrhosis

 

S-V

S-thal

BDL-V

BDL-thal

Body wt (g)

426 ± 10.8

410 ± 9.9

419 ± 11.3

399 ± 11.7

Absolute anterior tibialis wet wt (g)

1.43 ± 0.12

1.3  ± 0.21

0.72 ± 0.07#

0.99 ± 0.51

Relative anterior tibialis wet wt/body wt (mg/g,%)

0.0035 ± 0.0009

0.0032 ± 0.0004

0.0017 ± 0.0006#

0.0025 ± 0.0005*

Absolute gastrocnemius wet wt (g)

4.4 ± 0.006

4.19 ± 0.031

3.11 ± 0.03#

3.89 ± 0.081*

Relative gastrocnemius wet wt/body wt (mg/g,%)

0.0103 ± 0.0009

0.0102 ± 0.0002

0.0073 ± 0.0004#

0.0097 ± 0.0012*

Protein content (mg/g)

246 ± 21

239 ± 38

151 ± 9#

211 ± 10*

  1. #,##p < 0.05, 0.01 vs. S-V; *,**p < 0.05, 0.01 vs. BDL-V. Wt: weight.