Table 2 Baseline laboratory factors by DPP4a quartiles and their correlations with DPP4a.

From: Plasma DPP4 activity is associated with no-reflow and major bleeding events in Chinese PCI-treated STEMI patients

U/L

Total

Q1

Q2

Q3

Q4

P

Correlation

≤21.53

21.54–27.14

27.15–32.92

≥32.96

r

p

Lipid profile

Total cholesterol (mg/dL)

4.11 ± 1.04

3.97 ± 1.03

4.06 ± 1.03

4.07 ± 1.08

4.32 ± 1.01

0.01

0.13a

<0.01

Triglyceride (mg/dL)

1.56 ± 0.84

1.53 ± 0.71

1.55 ± 0.78

1.45 ± 0.78

1.68 ± 0.85

0.07

0.06a

0.11

HDL cholesterol (mg/dL)

1.05 ± 0.29

1.01 ± 0.28

1.03 ± 0.28

1.07 ± 0.29

1.09 ± 0.31

0.06

0.11a

0.01

LDL cholesterol (mg/dL)

2.53 ± 0.89

2.42 ± 0.85

2.50 ± 0.85

2.53 ± 0.86

2.67 ± 0.86

0.03

0.11a

<0.01

Coagulation profile

Thrombin time (sec)

16.60 (15.80–18.53)

16.30 (15.60–17.80)

16.70 (15.80–18.20)

16.70 (15.90–19.63)

16.90 (16.20–19.48)

<0.01

0.16b

<0.01

Prothrombin time (sec)

13.64 ± 1.40

13.74 ± 1.41

13.62 ± 1.23

13.66 ± 1.08

13.55 ± 1.80

0.67

−0.01a

0.83

APTT (sec)

37.85 (34.90–43.33)

38.10 (34.10–41.90)

38.00 (35.28–43.65)

38.05 (35.30–44.43)

37.60 (35.10–42.55)

0.79

0.02b

0.76

Fibrinogen (g/L)

3.75 ± 1.16

4.07 ± 1.35

3.91 ± 1.22

3.58 ± 1.01

3.45 ± 0.94

<0.01

−0.21a

<0.01

FPB (mmol/l)

6.97 ± 2.71

7.21 ± 2.86

7.00 ± 2.72

6.94 ± 2.90

6.72 ± 2.28

0.53

−0.05a

0.20

HbA1C (%)*

6.40 ± 1.38

6.61 ± 1.62

6.20 ± 1.16

6.49 ± 1.47

6.26 ± 1.14

0.13

−0.06a

0.27

peak CK-MB (ng/mL)

6.83 (1.83–131.76)

4.52 (1.74–76.99)

7.42 (1.86–162.03)

8.85 (1.88–154.60)

9.85 (1.82–215.43)

0.11

0.10b

0.01

peak cTNT (ng/mL)

0.65 (0.45–4.22)

0.62 (0.05–3.21)

0.53 (0.06–3.95)

0.56 (0.30–4.70)

1.08 (0.50–5.26)

0.64

0.05b

0.19

peak myoglobin (ng/mL)

49.84 (28.43–384.70)

44.19 (28.03–191.68)

38.09 (29.20–356.58)

49.84 (28.34–618.10)

127.60 (28.00–691.60)

0.12

0.14b

<0.01

pro-BNP (pg/mL)

653.90 (250.00–1581.00)

855.70 (250.15–1960.50)

659.20 (241.10–1486.00)

687.90 (282.70–1611.00)

553.70 (234.23–1396.00)

0.21

−0.07b

0.06

Creatinine (umol/L)

78.30 (68.20–90.18)

79.70 (65.30–95.80)

79.90 (66.45–91.75)

78.50 (70.28–91.65)

76.35 (67.45–85.50)

0.09

−0.07b

0.049

GGT (U/L)

32.80 (21.70–53.90)

30.40 (21.33–45.78)

30.60 (21.20–54.30)

31.00 (22.60–48.95)

38.00 (23.60–73.10)

<0.01

0.14b

<0.01

  1. APTT, activated partial thromboplastin time; BNP, brain natriuretic peptide; CK-MB, MB isoenzyme of creatine kinase; cTNT, cardiac troponin T; DPP4a, plasma dipeptidyl peptidase-4 activity; FPG, fasting plasma glucose; GGT, gamma-glutamyltransferase; HbA1c, hemoglobin A1c; HDL, high-density lipoprotein; LDL, low-density lipoprotein;
  2. aPearson correlation coefficients; bSpearman correlation coefficients.
  3. *HbA1c was only detected in 373 patients; Number of patients detected were 107 in Q1, 88 in Q2, 88 in Q3 and 89 in Q4.
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