Figure 7
Selected exogenous metabolites compounded with different antibiotics affect bacterial growth.
(A to F) The growth curves of A. hydrophila after treatment with tetracyclines by adding 0.5 μg/mL TET and 5 μg/mL CTC with different exogenous metabolites (i.e., citric acid in the gradient of 0, 0.078, 0.1563, and 0.3126 mM; succinic acid in the gradient of 0, 0.625, 1.25, and 2.5 mM; and malic acid in the gradient of 0, 0.3125, 0.625, and 1.25 mM). All growth kinetics of treated cells were recorded every hour for 12 hours by absorbance measurements at OD600 nm and 30 °C with the multimode detection platform. Abbreviations: tetracycline (TET), chlortetracycline (CTC).
