Table 1 Characteristics of studies on association between CD44 single nucleotide polymorphisms and cancers.

From: Associations of five polymorphisms in the CD44 gene with cancer susceptibility in Asians

Single Nucleotide Polymorphisms

Author

Year

Ethnicity

Cancers

Genotyping Method

Quality Score

Cases

Controls

Source of Controls

P for HWE in controls

Cases

Controls

AA

AB

BB

AA

AB

BB

rs13347

Yadava

2015

Indian

GBC

TaqMan, ARMS-PCR, PCR-RFLP

9

610

250

PB

0.62

378

201

31

162

80

8

rs13347

Wu

2015

Chinese

CRC

MALDI-TOF mass spectrometry

9

946

989

PB

0.28

416

441

89

578

348

63

rs13347

Weng

2015

Chinese

TCC

TaqMan

8

275

275

HB

0.15

138

111

26

143

117

15

rs13347

Liu

2015

Chinese

NSCLC

Taqman

8

234

468

HB

0.82

179

51

4

337

121

10

rs13347

Sharmaa

2014

Indian

GBC

TaqMan, PCR-RFLP

9

405

200

PB

0.57

293

104

8

154

42

4

rs13347

Lou

2014

Chinese

NPC

ABI 3730xl sequencing platform

8

287

507

HB

0.91

104

126

42

288

174

27

rs13347

Chou-1b

2014

Chinese

OSCC

TaqMan

7

599

561

HB

0.92

287

262

50

295

223

43

rs13347

Chou-2b

2014

Chinese

HCC

TaqMan

7

203

561

HB

0.92

110

72

21

295

223

43

rs13347

Xiao

2013

Chinese

NPC

MALDI-TOF mass spectrometry

9

906

943

PB

0.64

386

418

102

606

297

40

rs13347

Wu

2013

Chinese

AML

MALDI-TOF mass spectrometry

9

421

461

PB

0.34

163

196

62

254

171

36

rs13347

Tulsyan

2013

Indian

BC

ABI 7500 Real Time PCR system

8

258

241

HB

0.58

191

60

7

178

57

6

rs13347

Jiang

2012

Chinese

BC

MALDI-TOF mass spectrometry

9

1049

1157

PB

0.84

451

484

114

654

430

73

rs11821102

Wu

2015

Chinese

CRC

MALDI-TOF mass spectrometry

9

946

989

PB

<0.001

815

119

12

843

131

15

rs11821102

Weng

2015

Chinese

TCC

TaqMan

8

275

275

HB

0.92

234

39

2

222

50

3

rs11821102

Lou

2014

Chinese

NPC

ABI 3730xl sequencing platform

8

287

507

HB

0.35

252

27

1

439

54

3

rs11821102

Chou-1b

2014

Chinese

OSCC

TaqMan

7

599

561

HB

0.28

531

63

5

481

75

5

rs11821102

Chou-2b

2014

Chinese

HCC

TaqMan

7

203

561

HB

0.28

173

29

1

481

75

5

rs11821102

Xiao

2013

Chinese

NPC

MALDI-TOF mass spectrometry

9

906

943

PB

0.14

796

100

10

805

129

9

rs11821102

Wu

2013

Chinese

AML

MALDI-TOF mass spectrometry

9

421

461

PB

0.28

370

50

1

398

59

4

rs11821102

Jiang

2012

Chinese

BC

MALDI-TOF mass spectrometry

9

1049

1157

PB

0.22

912

125

12

997

151

9

rs10836347

Wu

2015

Chinese

CRC

MALDI-TOF mass spectrometry

9

946

989

PB

0.10

821

120

5

851

129

9

rs10836347

Lou

2014

Chinese

NPC

ABI 3730xl sequencing platform

8

287

507

HB

0.85

249

27

2

438

55

2

rs10836347

Chou-1b

2014

Chinese

OSCC

TaqMan

7

599

561

HB

0.15

522

73

4

487

69

5

rs10836347

Chou-2b

2014

Chinese

HCC

TaqMan

7

203

561

HB

0.15

180

23

0

487

69

5

rs10836347

Xiao

2013

Chinese

NPC

MALDI-TOF mass spectrometry

9

906

943

PB

0.31

785

118

3

792

147

4

rs10836347

Wu

2013

Chinese

AML

MALDI-TOF mass spectrometry

9

421

461

PB

0.93

364

55

2

404

55

2

rs10836347

Jiang

2012

Chinese

BC

MALDI-TOF mass spectrometry

9

1049

1157

PB

0.97

906

139

4

995

156

6

rs713330

Weng

2015

Chinese

TCC

TaqMan

8

275

275

HB

0.87

231

42

2

223

49

3

rs713330

Chou-1b

2014

Chinese

OSCC

TaqMan

7

599

561

HB

0.09

507

88

4

467

86

8

rs713330

Chou-2b

2014

Chinese

HCC

TaqMan

7

203

561

HB

0.09

167

36

0

467

86

8

rs713330

Xiao

2013

Chinese

NPC

MALDI-TOF mass spectrometry

9

906

943

PB

0.74

732

164

10

751

180

12

rs713330

Wu

2013

Chinese

AML

MALDI-TOF mass spectrometry

9

421

461

PB

0.39

341

74

6

371

87

3

rs713330

Jiang

2012

Chinese

BC

MALDI-TOF mass spectrometry

9

1049

1157

PB

0.39

865

172

12

950

194

13

rs1425802

Weng

2015

Chinese

TCC

TaqMan

8

275

275

HB

0.001

105

121

49

99

109

67

rs1425802

Chou-1b

2014

Chinese

OSCC

TaqMan

7

599

561

HB

< 0.001

197

249

153

194

235

132

rs1425802

Chou-2b

2014

Chinese

HCC

TaqMan

7

203

561

HB

< 0.001

70

75

58

194

235

132

rs1425802

Xiao

2013

Chinese

NPC

MALDI-TOF mass spectrometry

9

906

943

PB

0.11

270

450

186

299

442

202

rs1425802

Wu

2013

Chinese

AML

MALDI-TOF mass spectrometry

9

421

461

PB

0.08

126

204

91

122

248

91

rs1425802

Jiang

2012

Chinese

BC

MALDI-TOF mass spectrometry

9

1049

1157

PB

0.55

316

513

220

353

563

241

  1. PB: population-based. HB: hospital-based. PCR: polymerase chain reaction. RFLP: restriction fragment length polymorphism. ARMS: amplification refractory mutation system. HWE: Hardy-Weinberg equilibrium. GBC: gallbladder cancer. CRC: colorectal cancer. TCC: transitional cell carcinoma of urinary bladder. NSCLC: non-small cell lung cancer. NPC: nasopharyngeal carcinoma. OSCC: oral squamous cell carcinoma. HCC: hepatocellular carcinoma. AML: acute myeloid leukemia. BC: breast cancer.
  2. aContaining repeated data.
  3. bContaining the same population of controls.