Table 1 The basic information of the research subjects for the risk and prognosis studies.

From: Association of Polymorphisms in three pri-miRNAs that Target Pepsinogen C with the Risk and Prognosis of Gastric Cancer

Variables

For the risk study

For the prognosis study

AG vs. CON

GC vs. CON

Gastric cancer

death

Median survival time (M)

P

CON(%)

AG(%)

CON(%)

GC(%)

 

n = 862

N = 862

n = 729

n = 724

n = 357

n = 89

  

Gender

P = 0.846

P = 0.564

    

 Male

483(56.0)

487(56.5)

483(66.3)

490(67.7)

255

63

60.8 a

0.797

 Female

379(44.0)

375(43.5)

246(33.7)

234(32.3)

102

26

45.7 a

 

Age

P = 0.343

 

P = 0.562

     

 Mean ± SD

54.9 ± 9.2

55.4 ± 9.5

56.1 ± 9.2

56.4 ± 9.8

/

/

/

 

 Median

54

56

56

57

/

/

/

 

 Range

17–85

16–79

17–85

21–81

/

/

/

 

H. pylori

P < 0.001

 

P < 0.001

     

 Positive

241(28.0)

505(58.6)

201(27.6)

369(51.0)

/

/

/

 

 Negative

621(72.0)

41.4(36.5)

528(72.4)

355(49.0)

/

/

/

 

Smoking

n = 586

N = 548

n = 500

n = 333

    
 

P = 0.299

P = 0.183

    

 Ever Smoker

202(34.5)

173(31.6)

199(39.8)

148(44.4)

/

/

/

 

 Never Smoker

384(65.5)

375(68.4)

301(60.2)

185(55.6)

/

/

/

 

Drinking

n = 585

N = 547

n = 499

n = 296

    
 

P = 0.333

P = 0.044

    

 Drinker

147(25.1)

124(22.7)

146(29.3)

107(36.1)

/

/

/

 

 Nondrinker

438(74.9)

423(77.3)

353(70.7)

189(63.9)

/

/

/

 

Borrmann type

       

0.055

 Borrmann I–II

/

/

/

/

83

23

66.5 a

 

 Borrmann III–IV

/

/

/

/

274

66

53.8 a

 

Lauren type

       

0.234

 Intestinal type

/

/

/

/

120

25

59.9 a

 

 Diffuse type

/

/

/

/

231

61

59.3 a

 

 Non classified carcinoma

/

/

/

/

6

   

TNM stage

       

9.40 × 10−15

 I–II

/

/

/

/

171

12

73.5a

 

 III–IV

/

/

/

/

186

77

27

 

Depth of invasion

       

5.35 × 10−9

 T1 + T2

/

/

/

/

98

3

76.8 a

 

 T3 + T4

/

/

/

/

259

86

52.2 a

 

Lymph node metastasis

       

1.82 × 10−8

 positive

/

/

/

/

216

77

32

 

 negtive

/

/

/

/

141

12

71.5 a

 
  1. aMean survival time was provided when MST could not be calculated.