Figure 2: Titanium particles released from SLA titanium implants induce inflammatory responses in macrophages.
From: Scaling of titanium implants entrains inflammation-induced osteolysis

BMDMs were cultured for 24 hours with titanium particles that were released by ultrasonic scaling (Ti) and/or bacterial LPS (control). Saline was used as the control. IL1β, IL6 and TNFα expression levels were measured using RT-qPCR, normalized to β-actin and expressed as a fold-change relative to the control level. The data are shown as the mean ± SD of n = 5 for each condition. These data are from a representative experiment out of 5 *p < 0.05 versus control; **p < 0.05 versus LPS and the control.