Table 1 The correlation between PRKAR1A and E-cadherin immunostaining and clinicopathological features in 102 cases of lung adenocarcinoma tissues (χ2-test).

From: PRKAR1A is a functional tumor suppressor inhibiting ERK/Snail/E-cadherin pathway in lung adenocarcinoma

Variables

Case No.

PRKAR1A

E-cadherin

<3

≥3

P

<3

≥3

P

Age (year)

 <60

53

33

20

0.291

26

27

0.238

 ≥60

49

36

13

 

30

19

 

Gender

       

 male

61

37

24

0.066

32

29

0.545

 female

41

32

9

 

24

17

 

Smoking

 yes

64

46

18

0.277

36

28

0.837

 no

38

23

15

 

20

18

 

Differentiation

 Well and moderate

67

46

21

0.825

30

37

*0.006

 Poor and undifferentiation

35

23

12

 

26

9

 

TNM stage

 I–II

66

39

27

*0.015

30

36

*0.012

 III–IV

36

30

6

 

26

10

 

Size of tumor

       

 <3 cm

43

24

19

*0.034

12

34

*0.000

 ≥3 cm

59

45

14

 

47

12

 

Node metastasis

 no

30

8

22

*0.000

7

23

*0.000

 yes

72

61

11

 

49

23

 
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