Table 2 Top 30 candidate genes related to music identified by CE.

From: Convergent evidence for the molecular basis of musical traits

Gene information

Result

Number of studies where indicated

Gene symbol

Genomic location in humans

CE Score

Humans

Songbirds

Other

Practise*

Listening*

Ability*

EGR1

5q23-q31

0.219

29

1

13

19

7

Cortisol

0.169

14

2

13

1

FOS

14q24.3

0.149

1

15

3

7

13

4

FOXP2

7q31

0.102

12

2

13

6

ARC

8q24.3

0.067

8

1

4

3

Dopamine

0.059

1

3

3

4

6

1

BDNF

11p14.1

0.056

4

3

4

3

Noradrenalin

0.052

3

1

1

5

1

GRIN2B

12p13.1

0.049

1

4

1

3

2

3

SYT4

18q12.3

0.049

1

5

4

1

1

PHIP

6q14

0.047

2

3

1

2

2

MAPK10

4q22-q23

0.047

2

3

3

1

2

DRD1

5q34-q35

0.046

4

2

5

1

1

SNCA

4q21.3-q22

0.045

3

1

3

1

1

NR4A3

9q22

0.044

6

2

4

IRS2

13q34

0.044

6

3

3

ARHGAP24

4q22.1

0.043

3

1

2

1

2

MTMR2

11q22

0.043

1

4

3

1

1

NR4A2

2q22-q23

0.043

1

3

1

1

3

1

DUSP1

5q35.1

0.042

1

4

4

1

DUSP5

10q25

0.042

1

4

3

2

1

PKIA

8q21.13

0.041

1

4

3

1

1

PNISR

6q16.3

0.040

1

4

2

2

1

Estradiol

0.040

1

4

1

4

2

TET2

4q24

0.039

2

2

2

1

2

UBE2D3

4q24

0.039

2

2

3

2

FAM13A

4q22.1

0.039

2

2

2

1

2

NUDT9

4q22.1

0.039

2

2

3

2

DOPEY2

21q22.2

0.038

2

2

3

1

NTRK2

9q22.1

0.038

4

1

3

2

  1. CE score is calculated as weighted mean from the number of layers where the molecule has been detected. The following columns show the number of studies where the molecule has been detected, classified by species and subphenotypes. More information on the cellular location and music-related brain regions can be found from Supplementary Table S8. The full list of ranked molecules can be seen in Supplementary Data.
  2. *There can be multiple phenotypes per study or the study phenotype may belong to multiple subcategories.