Figure 6: CVID-AcT is characterized by lymphocyte activation, exhaustion and IL-10 serum elevation.

Markers of lymphocyte activation, exhaustion and senescence (A) and serum cytokine levels (B) in healthy controls, other CVID patients and Cluster AcT CVID groups. Asterisk (*) denotes a significant difference between the groups (adjustment p-value using the Benjamini & Yekutieli procedure).