Table 2 Oxidative stress assessment in blood and vascular walls.

From: Acetyl-11-Keto-β-Boswellic Acid Attenuates Prooxidant and Profibrotic Mechanisms Involving Transforming Growth Factor-β1, and Improves Vascular Remodeling in Spontaneously Hypertensive Rats

Groups

Serum

Thoracic aorta

SOD (U)

GPx (U)

MDA (nM/L)

SOD (U)

GPx (U)

MDA (nM/L)

WKY

202.83 ± 19.57

820.61 ± 97.59

7.01 ± 1.65

96.01 ± 7.47

362.71 ± 28.51

4.41 ± 0.50

SHR

130.90 ± 16.63###

636.04 ± 77.07##

11.52 ± 2.98##

58.39 ± 5.67###

297.53 ± 12.07###

6.85 ± 0.75###

AKBA 10 mg/kg

143.94 ± 14.34

688.59 ± 54.50

9.05 ± 2.29

69.27 ± 6.72*

313.36 ± 10.22

6.49 ± 0.45

AKBA 20 mg/kg

177.39 ± 18.64**

759.39 ± 54.28*

8.22 ± 1.48*

78.13 ± 8.32**

329.75 ±  ± 7.47**

6.05 ± 0.44**

AKBA 40 mg/kg

199.06 ± 18.04***

812.73 ± 72.77**

7.79 ± 1.53*

92.91 ± 9.43***

346.72 ± 11.82***

5.31 ± 0.70***

  1. The data are represented as mean ± SD (n = 5). ##P < 0.01, ###P < 0.001 vs. WKY group; *P < 0.05, **P < 0.01, ***P < 0.001 vs. SHR group.
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