Table 2 Results of gonadal hormone levels: effects of group, genotype and menstrual cycle phase.

From: The OPRM1 A118G polymorphism modulates the descending pain modulatory system for individual pain experience in young women with primary dysmenorrhea

 

PDM

Control

p Value

AA

G carrier

AA

G carrier

Phase

Group

Genotype

(n = 26)

(n = 35)

(n = 23)

(n = 42)

Estradiol (pg/mL)

Menstruation

32.9 (14.12)

33.4 (17.89)

30.2 (15.53)

37.2 (17.96)

0.000

0.653

0.166

Peri-ovulatory phase

146.9 (84.23)

157.5 (115.81)

151.8 (132.23)

142.8 (114.04)

0.370

0.770

Progesterone (ng/mL)

Menstruation

0.5 (0.46)

0.4 (0.25)

0.9 (2.50)

0.5 (0.30)

0.007

0.396

0.857

Peri-ovulatory phase

0.9 (1.38)

0.7 (0.79)

1.9 (3.23)

1.3 (2.78)

0.709

0.625

Testosterone (ng/mL)

Menstruation

0.4 (0.28)

0.3 (0.17)

0.4 (0.22)

0.4 (0.22)

0.000

0.830

0.743

Peri-ovulatory phase

0.5 (0.37)

0.5 (0.23)

0.4 (0.24)

0.5 (0.18)

0.862

0.707

  1. The data are presented as the means (SD). PDM, primary dysmenorrhea.