Table 3 Results of heat-pain threshold: effects of group, genotype and menstrual cycle phase.

From: The OPRM1 A118G polymorphism modulates the descending pain modulatory system for individual pain experience in young women with primary dysmenorrhea

 

PDM

Control

p Value

AA

G carrier

AA

G carrier

Phase

Group

Genotype

C7-dermatome

 Menstruation

43.7 (3.65)

44.4 (3.07)

46.0 (2.74)

45.0 (3.69)

0.231

0.024

0.938

 Peri-ovulatory phase

43.3 (3.04)

44.3 (2.95)

46.3 (2.20)

44.6 (3.59)

0.019

0.865

T11-dermatome

 Menstruation

42.8 (3.12)

43.4 (2.75)

44.7 (2.96)

43.8 (3.49)

0.599

0.130

0.831

 Peri-ovulatory phase

42.8 (2.99)

43.6 (2.69)

45.1 (2.83)

43.8 (3.66)

0.094

0.883

  1. Subjects who did not complete the thermal quantitative sensory test were excluded from respective calculations: 1 PDM subject with G allele during menstruation, 2 PDM subjects with AA homozygotes during the peri-ovulatory phase, 1 control with G allele during menstruation, and 3 controls with AA homozygotes during menstruation.
  2. The data are presented as the means (SD). PDM, primary dysmenorrhea.
Back to article page