Figure 1: Effect of estradiol treatment on the microarchitecture of the testis.
From: Effects of Elevated β-Estradiol Levels on the Functional Morphology of the Testis - New Insights
(A) Estradiol treated patients showed fatty degeneration within the surrounding connective tissue (→, PAS). (B) In comparison, the patients w/o estradiol treatment showed no vacuoles in their connective tissue (PAS). (C) Estradiol significantly decreased the diameter of the seminiferous tubules of the patients. Data are presented as an average of seminiferous tubule diameter (μm) of the patients with estradiol treatment (red) and w/o estradiol treatment (green). (*p < 0.05, 2-sided t-test). The decrease in diameter of the seminiferous tubules is seen when comparing Fig. 1A,B. (D) Sudan staining confirmed that the vacuoles seen in the estradiol treated patients contain fat (→).
