Figure 2: Metabolic ratios showing significant alterations in all examined cancer cell lines due to the contact with endothelial cells.

The box plot presents a significant increase in the metabolic ratios, which was observed over the entire experimental period in all cancer cell lines. The yellow color indicates control (cancer cells at time point 0, not co-cultured) and striped pattern indicates cancer cells co-cultured with endothelial cells at different time points.