Figure 3: Impact of endothelial cells on glycolysis, TCA cycle and glycosylation. | Scientific Reports

Figure 3: Impact of endothelial cells on glycolysis, TCA cycle and glycosylation.

From: Nesting of colon and ovarian cancer cells in the endothelial niche is associated with alterations in glycan and lipid metabolism

Figure 3

The glucose intake and lactate production same as TCA cycle metabolism were not significantly altered in all cancer cell lines. The significant metabolic alterations can be linked with modification in glycosylation patterns. Red reflects significant increase observed in all cancer cell lines at given time points in comparison with control. Green reflects significant decrease observed in all cancer cell lines in comparison with control (time point 0, highlighted in yellow). Gray indicates no significant changes observed for all cancer cell lines. The striped pattern reflects alterations identified as significant over the entire experiment. The significance level was p ≤ 3.49 × 10−04 (p ≤ 0.05/143).

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