Table 1 Baseline characteristics.

From: Predictors of Exercise-Induced Pulmonary Hypertension in Patients with Asymptomatic Degenerative Mitral Regurgitation: Mechanistic Insights from 2D Speckle-Tracking Echocardiography

 

All patients (n = 75)

Non-EIPH (n = 50, 66.7%)

EIPH (n = 25, 33.3%)

P value

Clinical characteristics

 Age, y

59.1 ± 13.1

56.6 ± 13.4

64.0 ± 11.2

0.01

 Male sex

56 (74.7)

37 (74.0)

19 (76.0)

0.85

 BMI, kg/m2

22.2 ± 3.2

21.9 ± 3.3

22.7 ± 3.2

0.33

 Heart rate, bpm

69.5 ± 10.9

69.0 ± 11.5

70.6 ± 9.8

0.54

 SBP, mmHg

132.7 ± 17.1

130.6 ± 14.3

136.9 ± 21.3

0.16

 DBP, mmHg

74.3 ± 10.1

74.0 ± 9.8

74.7 ± 10.8

0.72

 Log BNP, pg/mL

1.49 ± 0.32

1.46 ± 0.29

1.53 ± 0.37

0.31

Risk factors

 Hypertension

31 (41.3)

16 (32.0)

15 (60.0)

0.02

 Dyslipidemia

14 (18.7)

10 (20.0)

4 (16.0)

0.68

 Diabetes mellitus

0 (0)

0 (0)

0 (0)

-

Medications

 ACE-I/ARB

20 (26.7)

10 (20.0)

10 (40.0)

0.06

 β-blocker

6 (8.0)

2 (4.0)

4 (16.0)

0.07

 Calcium channel blocker

17 (22.7)

6 (12.0)

11 (44.0)

0.002

 Diuretic

13 (17.3)

6 (12.0)

7 (28.0)

0.08

 Statin

10 (13.3)

7 (14.0)

3 (12.0)

0.81

Etiology of mitral regurgitation

 Anterior leaflet prolapse

22 (29.3)

16 (32.0)

6 (24.0)

0.47

 Posterior leaflet prolapse

48 (64.0)

31 (62.0)

17 (68.0)

0.61

 Both leaflet prolapse

2 (2.7)

1 (2.0)

1 (4.0)

0.61

 Sclerotic change

3 (4.0)

2 (4.0)

1 (4.0)

1.00

  1. Data are expressed as mean ± SD or number (percentage), as appropriate.
  2. Abbreviations: ACE-I, angiotensin-converting enzyme inhibitor; ARB, angiotensin receptor blocker; BMI, body mass index; BNP, brain natriuretic peptide; DBP, diastolic blood pressure; EIPH, exercise-induced pulmonary hypertension; SBP, systolic blood pressure.