Table 1 Characteristics of the subjects according to SUA quartiles.

From: Serum uric acid levels are associated with obesity but not cardio-cerebrovascular events in Chinese inpatients with type 2 diabetes

Variables

Q1 (n = 733)

Q2 (n = 742)

Q3 (n = 740)

Q4 (n = 747)

p value

*p value

SUA (umol/l)

<257

257–311

312–374

>374

—

—

Age (years)

60 ± 12

59 ± 12

59 ± 13

59 ± 13

0.924

0.262

Male (n, %)

294 (40.1%)

392 (52.8%)

458 (61.9%)

532 (71.2%)

<0.001

<0.001

*DD (months)

72 (12–132)

84 (24–144)

72 (24–132)

72 (24–132)

0.314

0.198

Smoking (n, %)

161 (22.0%)

219 (29.5%)

218 (29.5%)

254 (34.0%)

<0.001

0.264

Alcohol (n, %)

77 (10.5%)

113 (15.2%)

123 (16.6%)

148 (19.8%)

<0.001

0.785

HTN (n, %)

308 (42.0%)

368 (49.6%)

414 (55.9%)

488 (65.3%)

<0.001

<0.001

Metformin (n, %)

367 (50.1%)

409 (55.1%)

427 (57.7%)

432 (57.8%)

0.003

<0.001

IIAs (n, %)

556 (75.9%)

546 (73.6%)

475 (64.2%)

502 (67.2%)

<0.001

<0.001

LLD (n, %)

163 (22.2%)

213 (28.7%)

231 (31.2%)

306 (41.0%)

<0.001

<0.001

AHAs (n, %)

276 (37.7%)

339 (45.7%)

374 (50.5%)

453 (60.6%)

<0.001

<0.001

SBP (mmHg)

130 ± 17

131 ± 18

133 ± 17

134 ± 17

<0.001

<0.001

DBP (mmHg)

79 ± 10

79 ± 9

81 ± 9

81 ± 10

<0.001

<0.001

BMI (kg/m2)

23.68 ± 3.47

24.49 ± 3.18

25.22 ± 3.31

26.18 ± 3.26

<0.001

<0.001

WHR

0.89 ± 0.07

0.91 ± 0.06

0.92 ± 0.06

0.93 ± 0.06

<0.001

<0.001

*FPG (mmol/l)

8 (6.3–10.3)

7.9 (6.3–9.7)

7.6 (6.1–9.3)

7.4 (6.1–9.3)

<0.001

<0.001

*2 h PPG (mmol/l)

14.4 (10.6–17.5)

13.5 (9.8–16.9)

13.2 (10–16.2)

13.2 (9.8–16.8)

0.008

0.048

HbA1C (%)

9.8 ± 2.51

9.25 ± 2.37

8.81 ± 2.4

8.6 ± 2.18

<0.001

<0.001

*FCP (ng/mL)

1.3 (0.77–1.9)

1.52 (0.88–2.32)

1.82 (1.18–2.52)

2.13 (1.43–3.09)

<0.001

<0.001

*2h C-P (ng/mL)

2.71 (1.54–4.45)

3.35 (1.85–5.06)

4.18 (2.43–5.62)

4.67 (2.94–5.8)

<0.001

<0.001

*TG (mmol/l)

1.18 (0.84–1.65)

1.34 (0.95–1.96)

1.46 (1.01–2.16)

1.86 (1.28–2.76)

<0.001

<0.001

TC (mmol/l)

4.65 ± 1.12

4.68 ± 1.16

4.67 ± 1.05

4.83 ± 1.2

0.009

<0.001

HDL ± C (mmol/l)

1.21 ± 0.32

1.15 ± 0.33

1.07 ± 0.26

1.02 ± 0.26

<0.001

<0.001

LDL ± C (mmol/l)

3.09 ± 0.94

3.1 ± 0.99

3.07 ± 0.89

3.13 ± 0.97

0.642

0.142

*ALT (U/l)

17 (12–26)

19 (13–28)

19.5 (14–31)

22 (15–36)

<0.001

<0.001

*Cr (μmol/l)

57 (49–68)

64 (55–76)

69 (59–81)

78 (66–96)

<0.001

<0.001

*24 h UAE (mg)

10 (6–22)

10 (6–21)

11 (6–29)

15 (7–65)

<0.001

<0.001

*eGFR (ml/min/1.73 m2)

125 (103–148)

111 (96–133)

106 (89–127)

93 (72–115)

<0.001

<0.001

*CRP (mg/l)

0.96 (0.37–2.57)

1.05 (0.44–2.49)

1.15 (0.49–2.77)

1.4 (0.67–3.55)

<0.001

0.106

  1. Values are expressed as the mean ± S.D, or median with interquartile range, or percentages.
  2. *Non-normal distribution of continuous variables.
  3. P-value: The p-values were not adjusted for sex for the trend.
  4. *P-value: The *p-values were adjusted for sex for the trend.
  5. Abbreviations: DD, diabetic duration; HTN, hypertension; LLDs, lipid-lowering drugs; AHAs, antihypertensive agents; IIAs, insulin or insulin analogues; UAE, urinary albumin excretion.
Back to article page