Figure 3: Quantification of copies of LCR22s paralogous sequences by ddPCR in control individuals and DGS/VCFS parents-of-origin.
From: An exploratory study of predisposing genetic factors for DiGeorge/velocardiofacial syndrome
(A) Mean L9 sequences (grey bars) and L9 pseudogene sequences (black bars) per haplotype. Dashed lines represent the limits of the normal range observed in controls (C1–C21). (B) ddPCR results showing different types of amplicons for L9 fosmid sequence. DG2F shows a single group of positive droplets, while DG5F shows a second group of positive droplets with lower fluorescence amplitude. (C) Mean K3 sequences per haplotype. Dashed lines represent the limits of the normal range observed in controls (C1–C6).
