Table 3 Association of MMP-2 Rs2287074 with skeletal fluorosis in Tibetans and Kazaks.

From: Matrix Metallopeptidase-2 Gene rs2287074 Polymorphism is Associated with Brick Tea Skeletal Fluorosis in Tibetans and Kazaks, China

Genotype

Tibetans (n = 308)

Kazaks (n = 290)

Cases

Controls

OR (95% CI)*

Cases

Controls

OR (95% CI)#

n (%)

n (%)

n (%)

n (%)

n = 123

n = 185

n = 98

n = 192

GG

66(53.7%)

77(41.6%)

1(Reference)

39(39.8%)

61(31.8%)

1(Reference)

AG

53(43.1%)

88(47.6%)

0.588(0.343, 1.007)

47(48%)

92(47.9%)

0.802(0.468, 1.373)

AA

4(3.3%)

20(10.8%)

0.174(0.053, 0.575)

12(12.2%)

39(20.3%)

0.462(0.214, 0.996)

  1. Note: *Adjusted for fluoride intake, urine fluoride, age, gender and altitude. #Adjusted for age. Bold font, p < 0.05.
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