Table 4 Pooled estimates of ORs (95% CI) for the association between MMP-2 Rs2287074 and skeletal fluorosis.

From: Matrix Metallopeptidase-2 Gene rs2287074 Polymorphism is Associated with Brick Tea Skeletal Fluorosis in Tibetans and Kazaks, China

Inheritance model

Cases/controls

OR

95% CI

P

I2

P for heterogeneity*

All subjects

 AG versus GG

221/377

0.741

0.52~1.055

0.096

0%

0.578

 AA versus GG

0.373

0.202~0.689

0.002

Age ≤ 45

 AG versus GG

40/144

0.751

0.365~1.544

0.436

0%

0.937

 AA versus GG

0.165

0.020~1.339

0.092

45 < age ≤ 65

 AG versus GG

129/183

0.592

0.362~0.969

0.037

31.0%

0.235

 AA versus GG

0.403

0.191~0.850

0.017

Age > 65

 AG versus GG

52/50

1.126

0.462~2.744

0.794

0%

0.894

 AA versus GG

0.168

0.031~0.902

0.038

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