Table 5 The correlation of MMP-2 Rs2287074 with skeletal fluorosis severity.
Genotype | No | Mild | Moderate | Severe | r | P* |
|---|---|---|---|---|---|---|
n (%) | n (%) | n (%) | n (%) | |||
n = 377 | n = 150 | n = 43 | n = 28 | |||
All subjects | ||||||
GG | 138(36.6%) | 64(42.7%) | 26(60.5%) | 15(53.6%) | −0.151 | <0.01 |
AG | 180(47.7%) | 71(47.3%) | 16(37.2%) | 13(46.4%) | ||
AA | 59(15.6%) | 15(10%) | 1(2.3%) | 0(0%) | ||
Tibetans | ||||||
GG | 77(41.6%) | 35(51.5%) | 19(59.4%) | 12(52.2%) | −0.148 | <0.01 |
AG | 88(47.6%) | 29(42.6%) | 13(40.6%) | 11(47.8%) | ||
AA | 20(10.8%) | 4(5.9%) | 0(0%) | 0(0%) | ||
Kazaks | ||||||
GG | 61(31.8%) | 29(35.4%) | 7(63.6%) | 3(60%) | −0.122 | 0.038 |
AG | 92(47.9%) | 42(51.2%) | 3(27.3%) | 2(40%) | ||
AA | 39(20.3%) | 11(13.4%) | 1(9.1%) | 0(0%) | ||
