Figure 3: Alterations in the brain morphology of Ada−/− mice. | Scientific Reports

Figure 3: Alterations in the brain morphology of Ada−/− mice.

From: Alterations in the brain adenosine metabolism cause behavioral and neurological impairment in ADA-deficient mice and patients

Figure 3

(a) Brain explants from Ada−/− mice are smaller in size as compared to Ada+/+ brains. Upper view of Ada+/+ and Ada−/− brains at PND19. (b) Volume of brain parenchyma assessed by MRI of Ada+/+ (n = 6) and Ada−/− (n = 5) mice at PND20; *p < 0.05. Hematoxylin and Eosin staining of the lateral ventricles of 3 weeks old (c) Ada+/+ and (d) Ada−/−; 10x.

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