Table 3 Relationship between rs2242652 in telomerase reverse transcriptase gene and ischemic stroke risk (adjusted by gender and age).

From: Polymorphisms in Telomere Length Associated TERC and TERT predispose for Ischemic Stroke in a Chinese Han population

Model

Genotype

Control (N, %)

Case (N, %)

OR (95% CI)

P

P a

AIC

BIC

Codominant

G/G

213 (71%)

190 (63.3%)

1.00

0.11

1

837.4

859.4

G/A

78 (26%)

101 (33.7%)

1.46 (1.02–2.08)

A/A

9 (3%)

9 (3%)

1.12 (0.44-2.88)

G/G

213 (71%)

190 (63.3%)

1.00

Dominant

G/A-A/A

87 (29%)

110 (36.7%)

1.42 (1.01–2.01)

0.044*

0.44

835.7

853.3

G/G-G/A

291 (97%)

291 (97%)

1.00

Recessive

A/A

9 (3%)

9 (3%)

1.00 (0.39–2.55)

1

1

839.7

857.3

G/G-A/A

222 (74%)

199 (66.3%)

1.00

Overdominant

G/A

78 (26%)

101 (33.7%)

1.45 (1.02–2.07)

0.038*

0.38

835.4

853

Log-additive

   

1.31 (0.97–1.77)

0.079

0.79

836.6

854.2

  1. *p-value ≤ 0.05 indicates statistical significance.
  2. Abbreviations: OR, odds ratio; CI, confidence interval; AIC, Akaike’s Information criterion; BIC, Bayesian Information criterion.
  3. ap value was adjusted by Bonferroni correction.
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