Table 4 Relationship between rs2853677 in telomerase reverse transcriptase gene and ischemic stroke risk (adjusted by gender and age).

From: Polymorphisms in Telomere Length Associated TERC and TERT predispose for Ischemic Stroke in a Chinese Han population

Model

Genotype

Control (N, %)

Case (N, %)

OR (95% CI)

P

P a

AIC

BIC

Codominant

A/A

132 (44%)

107 (35.7%)

1.00

0.038*

0.38

835.2

857.2

A/G

137 (45.7%)

145 (48.3%)

1.31 (0.93–1.85)

G/G

31 (10.3%)

48 (16%)

1.91 (1.14–3.21)

Dominant

A/A

132 (44%)

107 (35.7%)

1.00

0.036*

0.36

835.3

852.9

A/G-G/G

168 (56%)

193 (64.3%)

1.42 (1.02–1.97)

A/A-A/G

269 (89.7%)

252 (84%)

1.00

Recessive

G/G

31 (10.3%)

48 (16%)

1.65 (1.02–2.68)

0.04*

0.4

835.5

853.1

Overdominant

A/A-G/G

163 (54.3%)

155 (51.7%)

1.00

0.5

1

839.3

856.9

A/G

137 (45.7%)

145 (48.3%)

1.12 (0.81–1.54)

Log-additive

   

1.36 (1.07–1.73)

0.011*

0.11

833.3

850.9

  1. *p-value ≤ 0.05 indicates statistical significance.
  2. Abbreviations: OR, odds ratio; CI, confidence interval; AIC, Akaike’s Information criterion; BIC, Bayesian Information criterion.
  3. ap value was adjusted by Bonferroni correction.
Back to article page