Figure 3: Reactive Oxidant Species (ROS) production in hepatic venous neutrophils (HVN) with and without co-incubation of portal venous plasma (PVP) and portal venous neutrophils (PVN) with and without co-incubation with hepatic venous plasma (HVP).

Significantly higher ROS production was observed in PVN compared to HVN (****p < 0.0001). Co-incubation of HVN with PVP conferred a heightened ROS phenotype (****p < 0.0001). Conversely, co-incubation of PVN with HVP attenuated the heightened ROS phenotype (****p < 0.0001).