Figure 4: Influence of porins on temocillin activity.

(a) Cumulative MIC distribution of temocillin in a subset of the collection (n = 31) selected to cover the whole range of MICs and influence of the OpdK competitor vanillate (VNL 2 mM). (b) Fold reduction (log2 scale) in temocillin MIC in the presence of VNL, according to temocillin MICs for the same isolates. The graph shows the box and whiskers plot with 10–90 percentiles, with the red line connecting the medians.