Figure 7: Ablation of TRIP-Br2 promotes brown adipocytes thermogenesis.
From: Transcription regulator TRIP-Br2 mediates ER stress-induced brown adipocytes dysfunction
(a) mRNA expression of thermogenesis, fatty acid oxidation, and oxidative metabolism markers in WT and TRIP-Br2 KO brown adipocytes treated with vehicle or tunicamycin (1 μg/ml) for 24 h (n = 4). (b) mRNA expression of thermogenesis, and oxidative metabolism markers in WT and TRIP-Br2 KO brown adipocytes treated with vehicle or Rosiglitazone (1 μg/ml) for 24 h (n = 3). All qPCR data are normalized with TBP and presented as mean ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001 (vs WT-Ctrl); #p < 0.05; ##p < 0.01; ###p < 0.001 (vs WT-Tuni or WT-Rosi).
