Figure 4: aft1Δ and zap1Δ mutants have increased susceptibility to AMB, FLC and H2O2. | Scientific Reports

Figure 4: aft1Δ and zap1Δ mutants have increased susceptibility to AMB, FLC and H2O2.

From: Transcriptome and network analyses in Saccharomyces cerevisiae reveal that amphotericin B and lactoferrin synergy disrupt metal homeostasis and stress response

Figure 4

Growth of aft1Δ and zap1Δ strains compared to the S. cerevisiae haploid wild type (BY4741) background. Serial 10-fold dilutions of the strains are plated from left (1 × 106 cells/mL in 5 μL spot) to right on synthetic complete agar with AMB (0.5 μg/mL), FLC (32 μg/mL) or H2O2 (2 mM). Growth at 30 °C was recorded at 3 days (control, AMB, FLC) or 2 days for H2O2 treatment.

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