Figure 3: ABCA7 deficiency blocks CD1d trafficking. | Scientific Reports

Figure 3: ABCA7 deficiency blocks CD1d trafficking.

From: ATP Binding Cassette Transporter ABCA7 Regulates NKT Cell Development and Function by Controlling CD1d Expression and Lipid Raft Content

Figure 3

Co-localization by confocal microscopy of CD1d, Caveolin-1, and LAMP-1 on peritoneal macrophages harvested from WT and Abca7−/− mice (representative images). Frequency of co-localization of CD1d with LAMP-1 quantified from images from 200 cells (bar graph). Data are expressed as mean ± SEM. *p < 0.05, by unpaired, two-tailed Student’s t-test.

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