Table 1 PTM rates in crystallins of a human emulsified lens with nuclear cataract (NC++).

From: Tryptophan and Non-Tryptophan Fluorescence of the Eye Lens Proteins Provides Diagnostics of Cataract at the Molecular Level

No

Protein

PTM type

Residue PTM rate (%)

Average PTM protein PTM rate (%)

1

α-Crystallin A

R68 → ArgP

1.3

6.1

R112 → ArgP

0.7

R116 → ArgP

24.1

R1117 → ArgP

1.3

R119 → ArgP

41.0

2

α-Crystallin B

W60 → NFK

1.3

0.75

R22 → ArgP

1.6

10.7

R107 → ArgP

1.5

R116 → ArgP

2.5

R120 → ArgP

97

R123→ArgP

24.5

3

β-Crystallin A4

W54 → OH-Trp

0.5

0.4

W149 → OH-Kyn

0.8

W179 → OH-Trp

1.3

4

β-Crystallin B1

W216 → OH-Trp

7.3

1.3

W237 → NFK

0.7

R233 → ArgP

1.7

0.3

5

β-Crystallin B2

W59 → OH-Kyn

2.5

3.9

W85 → OH-Trp

2.1

W151→OH-Trp

9.1

R189 → ArgP

4.1

0.6

R191 → ArgP

0.7

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