Figure 3: Biochemical, biomechanical and cartilage-related gene analyses of in vitro engineered tissues at various time points. | Scientific Reports

Figure 3: Biochemical, biomechanical and cartilage-related gene analyses of in vitro engineered tissues at various time points.

From: Repair of osteochondral defects with in vitro engineered cartilage based on autologous bone marrow stromal cells in a swine model

Figure 3

All examinations of wet weight (A), GAG (B) contents, total collagen (C), total collagen II (D), Young’s modulus (F), expressions of cartilage-related genes (G–I), and hypertrophy-related genes (J–L), except for collagen I content (E), showed an increasing trend with in vitro induction time. Expression of cartilage-related genes in samples at 4 and 8 weeks were even higher than those found in native cartilage. The columns with different letters indicate statistical significance.

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