Figure 2: Microglial activation and astrogliosis in cortices of Hexb−/− mice during development. | Scientific Reports

Figure 2: Microglial activation and astrogliosis in cortices of Hexb−/− mice during development.

From: FcRγ-dependent immune activation initiates astrogliosis during the asymptomatic phase of Sandhoff disease model mice

Figure 2

(A) Immunostaining of coronal sections for CD68 (green) and Iba1 (red) in the cerebral cortices of Hexb+/− and Hexb−/− mice during development from 2 weeks to 3 weeks. (B) Immunostaining for GFAP (green) in the cerebral cortices of Hexb+/− and Hexb−/− mice during development from 2 weeks to 3 weeks. Insets (a–d) show magnified views of the boxed regions. Blue represents DAPI staining. Scale bar, 100 μm.

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